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This medication comes with important safety warnings that you should carefully consider. Be sure to discuss any concerns with your healthcare provider.

• Proper Use: It is crucial to follow your healthcare provider’s instructions when using topical lidocaine. Applying it more frequently or in larger amounts than directed can lead to an accumulation in your body, increasing the risk of severe side effects. Do not use topical lidocaine on infected or severely damaged skin without consulting your doctor, as these conditions may cause excessive absorption. Overuse can result in serious complications such as seizures, breathing difficulties, low blood pressure, a slow heart rate, and potential cardiac arrest. Seek immediate medical attention if you experience any of these symptoms.

• Methemoglobinemia Risk: Topical lidocaine, particularly 5% ointment and LiDORx 3% gel, can induce methemoglobinemia, a critical blood disorder that impairs oxygen delivery to your body. This risk is elevated in individuals with low glucose-6-phosphate dehydrogenase (G6PD) levels, a hereditary condition that affects red blood cell stability. Caution is advised if you are frequently exposed to oxidizing chemicals such as chlorine and hydrogen peroxide, which are common in household cleaning products and hair dyes. Methemoglobinemia symptoms can appear immediately or hours after application and include headache, fatigue, and bluish skin. Prompt medical intervention is necessary to prevent severe consequences like seizures, unconsciousness, and cardiac arrhythmias (rapid heartbeat, dizziness, shortness of breath).

Special populations at higher risk include individuals with a history of methemoglobinemia, G6PD deficiency, heart or lung issues, those under six months of age, and those exposed to oxidizing agents.

In case of overdose or if you experience any concerning symptoms, seek emergency medical assistance without delay.

When taking this medication, some individuals may experience common side effects that are generally mild but should be monitored. These include feeling lightheaded or dizzy, drowsiness, ringing in the ears, blurry or double vision, vomiting, and sensations of feeling hot or cold. You might also experience numbness, twitching, shaking, or even seizures. In rare cases, there could be a temporary loss of consciousness, trouble breathing, a slow heart rate, or low blood pressure.

Other side effects reported by users, though less common, include feelings of nervousness, overwhelming happiness, or confusion. If these symptoms become bothersome, it’s advisable to reach out to a healthcare provider for guidance.

Certain serious side effects, although rare, demand immediate medical attention. These include blood problems like methemoglobinemia, which presents with seizures, loss of consciousness, rapid heartbeat, difficulty breathing, dizziness, fatigue, and a blue discoloration of the skin. An excess of the drug in the body can lead to drowsiness, confusion, a slow heartbeat, breathing difficulties, and muscle control issues. Serious allergic reactions might manifest as facial swelling, breathing difficulties, speech troubles, throat tightening, rash, lightheadedness, and clammy skin. If such symptoms occur, seek emergency medical care promptly.