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When using Arikayce (amikacin), it is important to be aware of potential risks and necessary precautions. The following points highlight the critical safety warnings associated with this medication:

• Breathing and Lung Issues: Arikayce (amikacin) may increase the risk of serious breathing problems. Seek immediate medical attention if you experience new or worsening shortness of breath, fever, cough, wheezing, or if you cough up blood or blood-tinged sputum. Individuals with a history of lung issues, such as asthma or COPD, are at greater risk.

• Hypersensitivity Pneumonitis: Some individuals may develop an allergic lung reaction known as hypersensitivity pneumonitis. Symptoms include cough, shortness of breath, chest pain, weight loss, and unusual lung sounds. Contact your healthcare provider if you experience these symptoms, as you may need to discontinue the medication.

• Serious Allergic Reactions: Rare but severe allergic reactions, including anaphylaxis, can occur. Symptoms may include hives, difficulty breathing, dizziness, and facial or throat swelling. Seek emergency medical assistance if these symptoms arise.

• Hearing Damage: Arikayce (amikacin) could lead to ringing in the ears or permanent hearing loss. The risk increases if you are concurrently using medications like furosemide. Regular hearing tests may be necessary during treatment. Notify your healthcare provider if you notice hearing changes, dizziness, or balance issues.

• Kidney Injury: This medication may increase the risk of kidney damage, especially if you have pre-existing kidney conditions or are using other nephrotoxic drugs. Your healthcare team may monitor your kidney function through blood tests. Watch for signs such as reduced urine output or swelling in the legs and feet.

• Muscle Weakness: Individuals with neuromuscular conditions such as myasthenia gravis may experience muscle weakness, potentially affecting breathing. Report any muscle weakness to your healthcare provider immediately.

• Pregnancy Risk: Aminoglycoside antibiotics, including Arikayce (amikacin), may pose a risk to unborn babies, potentially causing deafness. Discuss the risks and benefits with your healthcare provider if you are pregnant or planning to become pregnant.

• Contraindications: Avoid using this medication if you have a known allergy to aminoglycoside antibiotics, such as tobramycin, as it may lead to serious adverse reactions.

Always consult with your healthcare provider for any concerns or questions regarding the use of Arikayce (amikacin).

This medication may cause several side effects, some of which are common and usually mild. You might experience hoarseness, cough, shortness of breath, muscle or joint pain, upper throat irritation, diarrhea, nausea, headache, and tiredness. These symptoms often resolve on their own, but if they persist or worsen, it is advisable to consult a healthcare professional.

There are other side effects that some individuals might encounter, such as fever, weight loss, vomiting, and chest discomfort. If you experience any of these, especially if they are severe, it is important to contact your healthcare provider for guidance.

In rare cases, more serious side effects can occur, which require immediate medical attention. These include signs of a serious allergic reaction such as rash, itching, swelling of the face or tongue, severe dizziness, and difficulty breathing. Additionally, any signs of hearing damage, such as ringing in the ears or hearing loss, as well as symptoms indicating bronchospasm like wheezing, chest pain, or tightness, should prompt urgent care.

While many people using this medication do not experience severe side effects, it is crucial to stay vigilant and seek medical help if any concerning symptoms arise. Your health and safety are of utmost importance, so do not hesitate to reach out to a healthcare provider if you have any questions or concerns about these side effects.