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Velcade (bortezomib) is a medication used to treat certain cancers, specifically multiple myeloma and mantle cell lymphoma in adults. It is administered by a healthcare professional either as an injection under the skin or directly into a vein. Velcade works as a proteasome inhibitor, which means it blocks proteasomes, the proteins responsible for breaking down unneeded proteins inside cancer cells. This blockage causes waste to accumulate in the cells, leading to the death of cancer cells. While effective, Velcade may cause side effects such as numbness and tingling in the hands and feet. Always consult your healthcare provider for advice tailored to your personal medical needs before starting treatment with Velcade.