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Cefotan, also known as cefotetan, is an antibiotic used to treat a variety of bacterial infections. It is commonly used for infections of the respiratory tract, urinary tract, skin, and bones, as well as for preventing infections during certain surgical procedures.

Cefotetan is a second-generation cephalosporin antibiotic that covers a broad range of bacteria. It is effective against many Gram-positive bacteria, including Streptococcus species and Staphylococcus aureus (excluding MRSA). It also covers several Gram-negative bacteria, such as Escherichia coli, Klebsiella species, Proteus mirabilis, and Haemophilus influenzae. Additionally, cefotetan is known for its activity against anaerobic bacteria, including Bacteroides fragilis.

Cefotetan is a second-generation cephalosporin.

Cefotetan is contraindicated in patients with a known hypersensitivity to cefotetan itself, any component of the formulation, or other cephalosporin antibiotics. Additionally, caution is advised in patients with a history of penicillin allergy due to potential cross-reactivity.

Cefotetan may cause side effects such as nausea, vomiting, diarrhea, and abdominal pain. Some individuals might experience allergic reactions, which can include rash, itching, or difficulty breathing. There is also a risk of more serious side effects like blood disorders, liver dysfunction, or seizures, although these are less common. It is important for individuals to contact their healthcare provider if they experience any severe or concerning symptoms.