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The following safety and warning information is crucial for anyone considering or currently using Mycophenolate (CellCept). It is essential to understand the potential risks and necessary precautions associated with this medication. Please review these details carefully and consult your healthcare provider with any questions or concerns.

• Infection Risk: Mycophenolate may impair your immune system, increasing the likelihood of serious infections. Notify your doctor immediately if you experience symptoms such as a persistent sore throat, fever, chills, cough, painful or urgent urination, or changes in urine output.

• Cancer Risk: Use of Mycophenolate can rarely lead to cancer, including lymphoma and skin cancer. Protect yourself from sun exposure by using sunscreen and wearing protective clothing. Report any symptoms such as swollen glands, unexplained weight loss, night sweats, changes in moles, or unusual skin growths to your doctor.

• Effects on Pregnancy: Mycophenolate is not safe during pregnancy due to the risk of miscarriage and birth defects. Reliable contraception is required for both men and women using this medication. Women must undergo a pregnancy test before starting the treatment and periodically during use.

• Blood Cell Count: The medication can lower red and white blood cell counts, as well as platelets, potentially leading to anemia, bleeding, and infections. Regular blood tests may be necessary to monitor blood cell levels.

• Gastrointestinal Issues: There is a risk of stomach bleeding and ulcers, especially if combined with other medications that cause bleeding. Seek immediate medical attention for symptoms like fainting, vomiting blood, blood in stools, or severe, persistent stomach pain.

• Genetic Conditions: Mycophenolate should be avoided in individuals with hypoxanthine-guanine phosphoribosyltransferase (HGPRT) deficiency, as it may exacerbate symptoms related to this condition.

• Inflammation: Rarely, Mycophenolate can cause inflammation. Symptoms include fever, joint or muscle pain, and changes in lab results. Report these symptoms promptly to your healthcare provider.

• Driving and Operating Machinery: Mycophenolate can cause drowsiness, dizziness, low blood pressure, and confusion, which may impair your ability to drive or operate machinery safely. Exercise caution and consult your provider if you experience these effects.

• Phenylketonuria (PKU) Consideration: The oral suspension form of Mycophenolate contains phenylalanine. Patients with PKU should inform their provider to receive a safer formulation.

• Contraindications: Do not use Mycophenolate if you are allergic to it or mycophenolic acid.

In case of an overdose, seek emergency medical assistance promptly. Always keep open communication with your healthcare provider to ensure safe use of Mycophenolate.

When taking this medication, you might experience some common side effects, which are generally mild and may include constipation, nausea, headache, diarrhea, vomiting, stomach upset, gas, dizziness, drowsiness, and trouble sleeping. In some cases, muscle, neck, or back pain, high blood pressure, swelling, fever, and high cholesterol may also occur. If these persist or worsen, it's advisable to consult with a healthcare provider.

There are less common side effects such as indigestion, depression, tremor, fast heart rate, low platelet count, and low blood magnesium levels. While these are less frequent, any persistent or bothersome symptoms should be discussed with your healthcare provider.

More serious side effects, though rare, require immediate medical attention. These include unusual tiredness, fast or irregular heartbeat, easy bleeding or bruising, swelling of the feet or ankles, joint or muscle pain, and symptoms of serious allergic reactions like rash, severe dizziness, and difficulty breathing. If you experience stomach or abdominal pain that doesn't subside, black stools, vomit resembling coffee grounds, chest pain, or shortness of breath, seek emergency medical care.

A rare but potentially fatal brain infection called progressive multifocal leukoencephalopathy (PML) can occur, with symptoms such as clumsiness, loss of coordination, sudden changes in thinking, difficulty speaking or walking, seizures, and vision changes. Additionally, serious infections presenting with fever, cough, difficulty breathing, diarrhea, or weakness should be treated as emergencies. Lastly, although very rare, the risk of bleeding and cancer is associated with this medication, warranting urgent medical evaluation if symptoms arise. Always communicate any new or worsening symptoms to your healthcare provider promptly.

When taking Mycophenolate (CellCept), it's important to be aware of potential interactions with other medications. Some drugs, such as natalizumab and rituximab, can lower your immune system's effectiveness or increase infection risk when used with Mycophenolate. Additionally, Mycophenolate may reduce the effectiveness of hormonal birth control methods like pills, patches, or rings, which could lead to pregnancy. It's advisable to consult your doctor about using a backup birth control method and report any unexpected spotting or breakthrough bleeding.

Certain medications, including Amoxicillin, Cholestyramine, Ciprofloxacin, and various hormonal contraceptives, may require dosage adjustments or special monitoring if used with Mycophenolate. Similarly, drugs like Cyclosporine, Lanthanum Carbonate, and Sevelamer may increase the risk of side effects, but might still be necessary for your treatment. Always inform your healthcare provider about all other medications or supplements you are taking to ensure safe and effective use of Mycophenolate.