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Endari is used to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older.

Yes, Endari is FDA approved. It was approved by the U.S. Food and Drug Administration in July 2017 for the treatment of sickle cell disease in patients aged five years and older.

Endari, which is L-glutamine oral powder, works by increasing the availability of free glutamine in the blood. This helps to reduce oxidative stress in sickle cell red blood cells, thereby improving their flexibility and reducing the frequency of sickle cell crises. By enhancing the redox potential, Endari helps to maintain the integrity of red blood cells and reduce the complications associated with sickle cell disease.

Endari is primarily indicated for the treatment of sickle cell disease in adult and pediatric patients aged five years and older. It is used to reduce the acute complications associated with the disease.

The cost of Endari can vary based on factors such as the pharmacy, location, and insurance coverage. Without insurance, the price can be quite high, often several thousand dollars for a month's supply. It is advisable for individuals to check with their specific pharmacy and insurance provider for the most accurate and up-to-date pricing information. Additionally, there may be patient assistance programs available to help reduce the cost.