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Enrofloxacin is a broad-spectrum antibiotic belonging to the fluoroquinolone class, commonly prescribed in veterinary medicine to treat various bacterial infections in animals. It is effective against a wide range of Gram-negative and some Gram-positive bacteria, including Escherichia coli, Staphylococcus species, and Mycoplasma species. Enrofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and repair, leading to bacterial cell death. Administered orally or via injection, it is used to manage infections of the respiratory and urinary tracts, skin, and other tissues. While generally well-tolerated, potential side effects include gastrointestinal upset, and in rare cases, neurological issues or joint cartilage damage in young, growing animals. Due to its potency and the risk of promoting antibiotic resistance, enrofloxacin should be used judiciously and only under the guidance of a veterinarian.