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The following safety and warning information is essential for those using Lumigan (bimatoprost). Please read thoroughly and discuss any concerns with your healthcare provider.

• Changes in Eye and Eyelid Color: Lumigan may lead to a darkening of the eyes and eyelids. This occurs due to increased melanin levels, which is the pigment responsible for eye color.

• Alterations in Eyelashes: During the use of Lumigan, you may experience longer, thicker, or more numerous eyelashes. These changes usually reverse once the medication is discontinued.

• Eye Inflammation and Swelling: Lumigan can cause or worsen eye inflammation, such as redness and swelling. It may also lead to macular swelling, affecting the retina's clarity of vision. This is particularly concerning for individuals with existing eye inflammation or damaged/missing lenses. If you experience eye discomfort or vision changes, consult your healthcare provider. Risks include current eye inflammation (e.g., uveitis) and damaged or absent eye lenses.

• Macular Edema: There is a risk of macular edema, which is the swelling of the retina and can alter vision by causing blurriness or dull color perception. Those with artificial lenses or a history of eye conditions may be more susceptible. Regular eye exams are recommended to monitor eye health. Contact your provider immediately if vision changes occur. Risks include a history of eye problems, age-related macular degeneration, genetic eye issues, eye surgeries, and the use of medications that induce macular edema.

• Risk of Bacterial Eye Infections: Contamination of Lumigan can lead to bacterial keratitis, an infection of the cornea. To prevent contamination, wash your hands before use, and avoid contact between the dropper and any surfaces, including your eyes and hands. Risks include corneal disease and eye surface injuries.

• Use with Soft Contact Lenses: The preservative benzalkonium chloride in Lumigan can be absorbed by soft contact lenses, potentially causing damage. Remove lenses prior to application and wait at least 15 minutes before reinserting them.

Contraindications:

• Allergy Considerations: Do not use Lumigan if you are allergic to any bimatoprost products. Always consult your healthcare provider if you have concerns about allergies or other contraindications.

When using this medication, some common side effects may occur, such as redness of the eye, increased eyelash growth, and eye itching, affecting up to 45% of users. These effects are usually mild, but if they persist or worsen, it's advisable to consult your healthcare provider. Other side effects that have been reported include dry eyes, a burning sensation in the eyes, a feeling of having something in the eye, redness around the eye, eye irritation, and blurry vision. Additionally, some individuals may experience symptoms resembling a common cold or an upper respiratory tract infection.

In some cases, the medication can lead to more noticeable changes, such as an increase in eyelash number, length, and thickness, and darkening of the eyelashes or eyelids. These changes may be permanent, but their long-term effects are still uncertain. If you experience any of these changes, regular eye exams are recommended to monitor their progress.

Although very rare, serious allergic reactions can occur. If you notice symptoms such as a rash, significant itching or swelling, particularly around the face, tongue, or throat, severe dizziness, or difficulty breathing, seek medical attention immediately. While serious side effects are uncommon, any vision changes or persistent eye pain should be promptly discussed with your healthcare provider. Regular monitoring and communication with your healthcare provider can help manage these side effects effectively.