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Phenelzine, commonly known by its brand name Nardil, is a medication prescribed for the treatment of depression in adults. It belongs to the class of drugs called monoamine oxidase inhibitors (MAOIs). Phenelzine works by blocking the action of two proteins, MAO-A and MAO-B, which are involved in breaking down mood-regulating chemicals such as dopamine, serotonin, and norepinephrine in the brain. By inhibiting these proteins, phenelzine helps to restore the balance of these natural substances, potentially improving mood and alleviating symptoms of depression. It is important to note that phenelzine is not typically the first choice for depression treatment due to its potential for numerous food and drug interactions, as well as side effects like sleepiness, weight gain, and sexual health issues. Always consult with a healthcare professional before starting or changing any medication regimen.