Phenylbutazone Coupons & Savings Card – Discount Prices from $1.01

Phenylbutazone, commonly known as "bute," is a nonsteroidal anti-inflammatory drug (NSAID) that was initially introduced in the 1950s for the treatment of inflammatory conditions such as rheumatoid arthritis and gout. It works by inhibiting cyclooxygenase (COX) enzymes, thereby reducing the production of prostaglandins, which are compounds involved in inflammation, pain, and fever. While phenylbutazone was effective in alleviating these symptoms, its use in humans has been largely discontinued due to serious side effects, including gastrointestinal ulcers, kidney damage, and blood disorders like aplastic anemia. Consequently, it is no longer approved for human use in the United States and many other countries. However, phenylbutazone remains widely used in veterinary medicine, particularly for managing pain and inflammation in horses. In these animals, it is administered to treat conditions such as lameness and arthritis, with careful dosing to minimize potential adverse effects.