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Darunavir, marketed as Prezista, is a medication used to manage HIV infection in individuals aged 3 years and older. It belongs to a group of medications called protease inhibitors, which work by blocking a protein known as protease. This action prevents the HIV virus from replicating and infecting healthy cells, thereby reducing the viral load in the body and supporting the immune system’s function. For optimal effectiveness, darunavir is typically administered alongside a "booster" such as ritonavir or cobicistat, which enhances its performance against the virus. While darunavir is not a cure for HIV, it helps lower the risk of HIV-related complications, including new infections and cancer, thereby improving the quality of life for those living with HIV. It is important to continue taking all prescribed HIV medications as directed by your healthcare provider to minimize the risk of transmitting the virus to others. Also, using effective barrier methods during sexual activities and avoiding the sharing of personal items that might be contaminated with blood or body fluids are crucial preventive measures. Please note that darunavir is not recommended for children under 3 years due to the potential for serious side effects. Some individuals may experience a skin rash during the first month of treatment, which typically resolves on its own. If you have a history of sulfa allergy, inform your healthcare provider, as darunavir contains a sulfa component. Always consult your doctor or pharmacist for personalized advice and guidance.