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The safety and warning information for Micardis HCT (telmisartan / HCTZ) is crucial for ensuring the well-being of patients. Please read the following details carefully and consult your healthcare provider if you have any questions or concerns.

• Pregnancy Risks: This medication can cause severe, potentially fatal, harm to an unborn baby, particularly affecting kidney development and function. It is vital to avoid pregnancy while taking this medication. Use effective birth control and consult your doctor if you are planning a pregnancy, become pregnant, or suspect you might be pregnant.

• Low Blood Pressure: There is a risk of experiencing a significant drop in blood pressure, which may lead to dizziness, fatigue, or lightheadedness. This is more likely when beginning treatment, increasing the dose, if dehydrated, or when using high doses of diuretics. To prevent low blood pressure, stay hydrated and rise slowly from sitting or lying positions. Contact your healthcare team if you experience severe symptoms or suffer any falls.

• Kidney Function: While ARBs in this medication can protect the kidneys, they may also impair kidney function in some individuals, particularly those with severe heart failure, existing kidney issues, or those on medications that affect the kidneys. Notify your prescriber if you notice any changes in urination.

• Electrolyte and Metabolic Changes: The medication can alter levels of electrolytes like sodium, potassium, and magnesium, as well as affect blood sugar, cholesterol, and triglyceride levels. Be aware of interactions with other medications that might exacerbate these changes.

• Allergic Reactions: There is a possibility of allergic reactions, especially in individuals with a history of allergies or asthma. Symptoms may include rash, itching, hives, breathing difficulties, or facial swelling. Seek medical advice if any of these occur.

• Vision Issues: Some individuals may experience vision changes or eye pain shortly after starting the medication. Report these symptoms immediately to your prescriber and discontinue use to avoid potential permanent vision loss.

• Lupus: This medication can trigger or worsen lupus symptoms such as fatigue, joint pain, or a rash across the cheeks and nose. Consult your healthcare provider if you have a history of lupus or experience these symptoms.

Contraindications: This medication should not be used if you are unable to urinate or if you are taking aliskiren (Tekturna) and have diabetes. Always discuss any pre-existing conditions or medications with your healthcare provider before starting Micardis HCT.

Common side effects:

• Dizziness
• Lightheadedness
• Tiredness
• Diarrhea
• Upper respiratory tract infections

Less common but important to monitor:

• Swelling of the sinuses
• Muscle cramps
• Nausea
• Vomiting
• Flu-like symptoms
• Sore throat
• Redness
• Upset stomach

Serious side effects:

• Dangerously low blood pressure
• Kidney issues
• Abnormal electrolyte levels
• Vision problems
• Severe allergic reactions
• Changes to the skin

Interactions with high risk of serious adverse effects and should be avoided:

• aliskiren
• dofetilide
• lithium
• ACE inhibitors (benazepril, lisinopril)
• birth control pills containing drospirenone

Interactions with moderate risk that may require dose adjustment, closer monitoring, or timing changes:

• sparsentan
• NSAIDs (ibuprofen, naproxen)

Interactions with low risk that usually do not require a change in therapy:

• cough-and-cold remedies
• diet pills