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When considering the use of Vraylar (cariprazine), it is crucial to be aware of potential risks and necessary precautions to ensure patient safety. Below is a summary of key safety information:

• Increased Risk in Dementia Patients: Older adults with dementia-related psychosis should not use Vraylar due to a heightened risk of death, often caused by heart issues, stroke, or infections. Discuss alternatives with your healthcare provider if this condition applies.

• Suicidal Thoughts and Behaviors: Individuals 24 years old or younger, or those taking other antidepressants, may experience an increased risk of suicidal thoughts and behaviors. Be vigilant for changes in mood or behavior and consult your healthcare provider if concerns arise.

• Neuroleptic Malignant Syndrome (NMS): Vraylar can cause NMS, a serious condition that may be fatal. Symptoms include high fever, rapid heart rate, full body stiffness, and confusion. Seek immediate medical attention if these occur.

• Metabolic Changes: This medication can increase blood sugar, cholesterol, and cause weight gain. Those with diabetes or high cholesterol should monitor for symptoms like extreme hunger, thirst, frequent urination, or fruity-smelling breath.

• Movement Disorders: Vraylar may lead to tardive dyskinesia, characterized by uncontrollable muscle movements. To minimize risk, use the lowest effective dose and seek medical help if unusual movements develop.

• Infection Risk: The medication can reduce white blood cell count, heightening infection risk. Regular blood tests may be necessary. Report symptoms like fever, weakness, or sore throat to your healthcare provider.

• Risk of Falls: Vraylar can cause dizziness and low blood pressure, increasing the fall risk, especially in older adults or those with heart issues. Stand up slowly and consult your provider if dizziness persists.

• Temperature Regulation Issues: The drug may impair your ability to regulate body temperature. Stay hydrated and avoid overheating.

• Swallowing Difficulties: Rarely, Vraylar can affect throat muscles, causing swallowing difficulties. Chew food thoroughly and swallow carefully.

• Seizure Risk: Patients with a history of seizures or related conditions should inform their healthcare provider before starting Vraylar.

Always discuss your medical history and any concerns with your healthcare provider to ensure Vraylar is safe for you. In case of an overdose or any severe reactions, seek emergency medical attention immediately.

When taking this medication, some common side effects may include dizziness, lightheadedness, drowsiness, nausea, tiredness, excess saliva, drooling, blurred vision, weight gain, and constipation. These effects are generally mild, but if they persist or worsen, it is advisable to consult your healthcare provider. Rising slowly from sitting or lying positions can help minimize dizziness and lightheadedness, reducing the risk of falls.

Less frequently, individuals may experience headache, restlessness, trouble sleeping, stomach pain, toothache, diarrhea, agitation, anxiety, indigestion, vomiting, and dizziness. While these are not as common, they should be brought to your healthcare provider's attention if they occur.

Serious side effects, although rare, require immediate medical attention. These include symptoms of a stroke such as numbness or weakness on one side of the body, loss of balance, headache, blurred vision, and difficulty speaking. Neuroleptic malignant syndrome (NMS) can manifest as high fever, sweating, confusion, stiffness, and blood pressure changes. Extremely high blood sugar levels may cause increased hunger or thirst, frequent urination, stomach pain, weakness, and fruity-smelling breath.

Additionally, uncontrolled muscle movements, known as tardive dyskinesia, may occur. This includes involuntary movements of the face and limbs, such as tongue protrusion and mouth puckering. Other serious side effects include suicidal thoughts or behaviors, seizures, and fainting spells that could lead to falls. A severe allergic reaction, though very rare, demands urgent medical evaluation if you notice rash, itching, swelling, severe dizziness, or difficulty breathing. Always consult your healthcare provider if you notice any unusual symptoms.