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This medication contains dextroamphetamine and requires careful use due to potential risks and side effects. Below are key safety considerations and warnings that should be reviewed before starting treatment. Always consult your healthcare provider if you have any concerns or questions.

• Risk of Misuse and Dependence: Dextroamphetamine can be habit-forming and may lead to misuse or dependence, especially in individuals with a history of substance abuse or mental health disorders. Misusing this medication or taking it in a manner not prescribed can result in serious side effects, including increased heart rate, high blood pressure, aggressive behavior, and even thoughts of self-harm. Always follow the prescribed dosage and schedule.

• Serious Cardiovascular Concerns: Use of dextroamphetamine is associated with potential heart-related risks, such as sudden death, stroke, or heart attack, even at recommended doses. It may elevate blood pressure and heart rate. Inform your healthcare provider if you have any history of heart problems before starting this medication. Report any chest pain, fainting, or irregular heartbeat to your provider immediately.

• Behavioral and Psychological Effects: The medication may exacerbate or induce mental health issues such as hallucinations, aggressive behavior, or mania. Those with pre-existing mental health conditions, like bipolar disorder or psychotic episodes, should be closely monitored. Notify your healthcare provider if you experience any unusual behavioral changes.

• Impact on Growth in Children: Dextroamphetamine might slow growth in children. Regular monitoring of growth parameters by a healthcare provider is recommended. If growth concerns arise, treatment adjustments may be necessary.

• Blood Circulation Issues: Some users may experience circulation-related problems, such as Raynaud's phenomenon, resulting in cold, numb, or painful fingers and toes. Contact your healthcare provider if you notice these symptoms.

• Potential for Serotonin Syndrome: There is a rare risk of serotonin syndrome, particularly when dextroamphetamine is combined with other serotonin-affecting drugs like certain antidepressants or migraine medications. Symptoms include rapid heart rate, sweating, muscle stiffness, fever, and confusion. Seek immediate medical help if these symptoms occur.

• Skin Sensitivity Reactions: The medication can cause skin reactions such as dry or itchy skin. Severe reactions may include redness with swelling or blisters. Consult your provider if severe skin reactions develop.

Contraindications:

• Do not use if you have a severe allergy to amphetamines.
• Avoid if you are currently taking or have recently taken MAOIs, linezolid, or methylene blue within the past 14 days.

In case of overdose, seek emergency medical attention immediately. Always communicate with your healthcare provider about any existing conditions, medications, or supplements you are taking to avoid harmful interactions.

When using this medication, you may experience some common side effects that are typically mild, such as nervousness, trouble sleeping, loss of appetite, weight loss, dizziness, nausea, vomiting, and headache. Additionally, mild irritation or discomfort at the application site may occur. These effects often resolve on their own, but if they persist or worsen, it is advisable to consult a healthcare provider.

It is important to monitor your blood pressure while on this medication, as it may increase. If you notice a significant rise in your readings, inform your healthcare provider promptly. Other possible effects include irritability and fast heart rate, which should also be communicated to your healthcare provider if they occur.

More serious side effects, although rare, require immediate medical attention. These include signs of blood flow issues in the fingers or toes, such as coldness, numbness, or pain, as well as severe allergic reactions characterized by rash, swelling, or difficulty breathing. Additionally, watch for symptoms of serotonin syndrome, which include fast heartbeat, hallucinations, and severe dizziness. Seek urgent medical care if you experience any heart-related problems like a heart attack, brain-related issues such as seizures or stroke, or mental health changes including mood swings or hallucinations.

If you notice any unusual effects not listed, or if you have concerns about side effects, contact your healthcare provider for guidance.

Avoid taking MAO inhibitors (such as isocarboxazid, linezolid, methylene blue, phenelzine, and others) with this medication, as it can lead to a serious and potentially fatal reaction. It is recommended to stop MAO inhibitors at least two weeks before starting this drug. Consult your doctor on when to begin or cease using this medication safely.

Inform your pharmacist about all the products you are using, especially if they contain ingredients that might increase your heart rate or blood pressure, such as certain cough-and-cold remedies or diet aids.

There is an increased risk of serotonin syndrome when this medication is taken alongside other drugs that elevate serotonin levels. This includes some antidepressants (like SSRIs such as fluoxetine and paroxetine, or SNRIs like duloxetine and venlafaxine), as well as substances like MDMA and St. John's wort. This risk is heightened when starting or increasing the dose of these drugs.

Dextroamphetamine is closely related to amphetamine and lisdexamfetamine; do not use these medications concurrently with dextroamphetamine.

This drug may interfere with certain lab tests, such as blood and urine steroid levels or brain scans for Parkinson's disease, potentially leading to inaccurate results. Ensure all your healthcare providers and laboratory personnel are aware that you are taking this medication.