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Acamprosate is a medication prescribed to support individuals with alcohol use disorder in maintaining abstinence from alcohol. It is most effective for adults who have already stopped drinking. The drug functions by modulating the N-methyl-D-aspartate (NMDA) receptors, helping to restore the balance of certain neurotransmitters in the brain, such as gamma-aminobutyric acid (GABA) and glutamate. This action helps to reduce the craving for alcohol. Acamprosate is typically taken orally three times a day. Some common side effects include diarrhea, trouble sleeping, and nervousness. It is available in generic form, as the brand name Campral has been discontinued. Before beginning treatment with Acamprosate, it is important to cease alcohol consumption, as the medication is not effective for those who continue to drink while taking it. Always consult with a healthcare professional before starting any new medication.