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When using this medication, it is important to be aware of potential risks and take necessary precautions. Below are essential safety warnings and instructions to consider:

• Abnormal Sleep Behaviors: This medication may lead to unusual activities during sleep, such as sleepwalking, sleep-driving, or eating while not fully awake. These behaviors can be dangerous and are often not remembered afterward. If you or anyone observes such activities, discontinue use and consult your healthcare provider immediately. Avoid taking this medication if you have experienced such reactions.

• Daytime Drowsiness and Decreased Alertness: Be cautious as this medication can cause drowsiness, dizziness, and reduced alertness during the day. The risk increases when combined with alcohol, benzodiazepines, opioids, or tricyclic antidepressants. Inform your healthcare provider if you are using these substances, as dosage adjustments may be necessary.

• Severe Allergic Reactions: In rare cases, severe allergic reactions, such as swelling of the tongue, lips, throat, or mouth, can occur. Symptoms may also include difficulty breathing, nausea, or vomiting. Seek emergency medical attention if you experience any signs of an allergic reaction.

• Behavioral and Mood Changes: This medication may cause unusual thoughts, changes in behavior, or mood disturbances, including aggression or hallucinations. Report any such changes to your healthcare provider for evaluation.

• Slowed Breathing: The medication can cause respiratory depression, particularly in individuals with sleep apnea. If you notice any changes in your breathing, contact your healthcare provider, as alternative treatments may be necessary.

• Liver Health Considerations: For those with liver conditions, this medication might not be processed efficiently, increasing the risk of side effects. It is not recommended for individuals with severe liver issues. Inform your healthcare provider about any liver problems before beginning treatment.

• Withdrawal Symptoms: Long-term use may lead to tolerance and dependence. Abrupt cessation or dose reduction can result in withdrawal symptoms such as nausea, sweating, anxiety, and tremors. Discuss any withdrawal symptoms with your healthcare provider.

• Contraindications: Do not use this medication if you have experienced abnormal sleep behaviors related to its use or similar medications.

Always communicate openly with your healthcare provider regarding your medical history and any concerns about using this medication.

When taking this medication, some individuals may experience dizziness, headache, sleepiness, or diarrhea. These common side effects are generally mild but should be monitored. If they persist or worsen, consult your healthcare provider.

Other side effects that have been reported include nausea, dry mouth, back pain, flu-like symptoms, chest pain, fatigue, lightheadedness, depression, abnormal dreams, memory loss, stomach pain, constipation, sinus infection, sore throat, and rash. While these are less common, it is important to discuss them with your healthcare provider if they occur.

More serious side effects, although rare, demand immediate medical attention. These include dangerous sleep behaviors such as sleepwalking or sleep driving, slowed brain activity leading to confusion or coma, and trouble breathing characterized by shallow or slow breaths. A serious allergic reaction may manifest as an itchy rash, swelling, or breathing difficulties. Additionally, any thoughts of suicide or severe mood changes should be addressed urgently.

It is essential to seek medical advice if you experience any of the side effects mentioned, especially the more severe ones. Monitoring your health and communicating with your healthcare provider can help manage any issues that arise during treatment.

When taking Zolpidem, it's important to be aware of potential drug interactions. Certain medications, such as sodium oxybate and other similar compounds like Calcium, Magnesium, and potassium oxybate, should generally be avoided with zolpidem. These combinations might require your doctor to adjust your treatment plan.

Additionally, medications that affect how zolpidem is processed in your body, like azole antifungals (e.g., Ketoconazole), Rifampin, and herbal supplements like St. John's Wort, can alter its effectiveness. Using zolpidem with these substances may necessitate dose adjustments.

The risk of experiencing severe side effects, such as slow or shallow breathing and extreme drowsiness, is higher if zolpidem is combined with substances that also cause drowsiness or breathing difficulties. This includes opioid pain relievers (e.g., codeine, hydrocodone), alcohol, marijuana, other sleep or anxiety medications (e.g., Alprazolam, Lorazepam, zopiclone), muscle relaxants (e.g., Carisoprodol, Cyclobenzaprine), and antihistamines (e.g., Cetirizine, diphenhydramine). Always inform your healthcare provider about all the medications and supplements you're taking, including prescribed, over-the-counter, and herbal products.

Lastly, check the labels on all your medications, such as those for allergies or colds, as they might contain ingredients that cause drowsiness. Consult your pharmacist to ensure safe use of these products alongside zolpidem.