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The safety and warning information for PEG 3350/electrolytes bowel prep is essential for ensuring safe use. Please review the following points carefully and discuss any concerns with your healthcare provider:

• Dehydration and Electrolyte Imbalance: This medication can lead to significant fluid loss and imbalanced electrolytes, potentially causing severe health issues like kidney problems, heart irregularities, and seizures. Ensure proper hydration and correct any electrolyte disturbances before using this medication. Contact your healthcare provider if you experience symptoms of dehydration, such as dizziness, headache, or dark urine, as they may need to check your electrolyte and kidney function.

• Cardiac Concerns: Rare but serious heartbeat irregularities (arrhythmias) can occur. Individuals with a history of heart conditions should inform their healthcare provider, as monitoring before and after use may be necessary. Watch for symptoms like chest fluttering, difficulty breathing, or chest pain.

• Seizure Risk: Imbalances in body fluids and electrolytes may lead to fainting or seizures, even in those without a prior history. Maintaining hydration is crucial to minimize this risk. Seek medical attention immediately if you feel faint or confused.

• Kidney Damage: Those with pre-existing kidney conditions should consult their provider to choose the appropriate brand of bowel prep. The risk of kidney damage increases with concurrent use of certain medications like diuretics, ACE inhibitors, or NSAIDs. Adequate water intake is important to prevent dehydration and kidney issues.

• Colon Damage: Osmotic laxatives can cause colon damage, including ulcers. Avoid using stimulant laxatives simultaneously. Inform your provider of any gastrointestinal conditions like ulcers or inflammation before use, as an alternative treatment may be necessary.

• Choking Hazard: Large volumes of liquid must be consumed with this preparation. Those with swallowing difficulties or compromised gag reflexes should exercise caution to prevent inhalation into the lungs. Avoid mixing with starch-thickened liquids. Consult your provider for alternative options if swallowing is problematic.

• Special Populations: Individuals with low glucose-6-phosphate dehydrogenase (G6PD) or phenylketonuria (PKU) must use Moviprep and Plenvu cautiously due to their sodium ascorbate and ascorbic acid content, which can damage red blood cells.

Contraindications: Do not use this medication if you have conditions such as gastrointestinal obstruction, bowel perforation, toxic colitis, toxic megacolon, gastric retention, or ileus, as it may pose significant health risks. Always consult your healthcare provider if any of these conditions apply to you.

When taking this medication, you might experience some common side effects such as nausea, bloating, feelings of fullness in the stomach or abdomen, and sometimes vomiting or stomach cramps. These are generally mild and should not be a cause for concern, but if they persist or worsen, it is advisable to consult your healthcare provider. Other mild effects can include anal irritation, shivering, trouble sleeping, increased hunger and thirst, and tiredness, particularly with certain formulations like Moviprep.

There are other side effects that, while less common, may occur. These include headaches, upper stomach bleeding, choking, and changes in electrolytes. If you encounter any of these, it is important to speak with your healthcare provider, especially if they are severe.

On a more serious note, there are rare but significant side effects that require immediate medical attention. These include severe stomach or abdominal pain, bloody vomit or stools, rectal bleeding, seizures, and signs of kidney issues such as reduced urine output or swelling in the legs. Heartbeat irregularities and electrolyte imbalances, which may present as dizziness, fainting, or a fast heart rate, are also serious concerns that necessitate urgent care. Additionally, a very serious allergic reaction is rare but possible, characterized by rash, severe dizziness, or difficulty breathing. If you notice any symptoms of a serious allergic reaction, seek medical help right away.

This is not an exhaustive list of potential side effects, so if you notice any other unusual symptoms, contacting your healthcare provider is recommended.