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Niacin, also known as vitamin B3, is a versatile medication utilized for several health purposes. It is primarily prescribed to prevent and treat niacin deficiency, a condition that can arise from poor diet, certain medical conditions like alcohol abuse and malabsorption syndrome, or prolonged use of specific medications, such as isoniazid. Symptoms of niacin deficiency include diarrhea, dementia, swollen tongue, and peeling red skin. Niacin plays a crucial role in the body's metabolism, aiding in the creation and breakdown of essential compounds for maintaining health. Additionally, Niacin ER, a prescription form of niacin, is used to manage high cholesterol and triglyceride levels. While it is not the first-choice treatment for these conditions, it can be particularly beneficial for individuals with a history of heart attacks or coronary artery disease, as it helps reduce the risk of repeated heart attacks and slows plaque buildup in arteries. It is also an effective treatment for severely high triglycerides in individuals at risk of pancreatitis. Niacin ER functions by inhibiting the release of fats from fatty tissue and reducing cholesterol production in the liver. It activates pathways that remove triglycerides, effectively lowering LDL ("bad") cholesterol and triglyceride levels while increasing HDL ("good") cholesterol. When taking niacin, it's important to follow your healthcare provider's instructions carefully, as improper use can lead to side effects like flushing and stomach upset. Always check the product label for ingredients, as formulations may change, and similar product names might indicate different purposes. Niacin is available over-the-counter for treating vitamin B3 deficiency, but it should not be substituted with niacinamide (nicotinamide) without medical advice. Consult your healthcare provider to ensure safe and effective use tailored to your health needs.