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Polymyxin B is an antibiotic used to treat infections caused by certain types of bacteria, particularly Gram-negative bacteria. It is often used for infections such as those of the urinary tract, meninges, and bloodstream, especially when other antibiotics are ineffective. It is also used topically for skin and eye infections.

Polymyxin B is considered a potent antibiotic, particularly effective against Gram-negative bacteria. It is often used for infections caused by multidrug-resistant organisms. However, due to potential nephrotoxicity and neurotoxicity, its use is typically reserved for severe infections where other antibiotics are not effective.

Polymyxin B can be used as part of a combination antibiotic eye drop to treat bacterial conjunctivitis, commonly known as pink eye, if it is caused by bacteria. However, it is important for an individual to consult a healthcare provider to determine the cause of the conjunctivitis and to receive appropriate treatment.

Polymyxin B, often referred to as poly B, can have several side effects. Common side effects include nephrotoxicity, which can lead to kidney damage, and neurotoxicity, which may cause symptoms such as dizziness, numbness, or tingling. Other potential side effects include respiratory issues, fever, rash, and itching. It is important for patients to be monitored closely by healthcare professionals while receiving this medication.

Polymyxin should generally be avoided by individuals with a known hypersensitivity or allergy to polymyxin or any of its components. It should also be used with caution in patients with renal impairment, neuromuscular disorders, or those who are pregnant or breastfeeding, unless the potential benefits outweigh the risks. It is important for patients to consult with their healthcare provider before starting polymyxin to ensure it is safe for their specific condition.