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Avanafil, marketed under the brand name Stendra, is a medication designed to treat erectile dysfunction (ED) in men. This drug functions as a phosphodiesterase 5 (PDE5) inhibitor. By blocking the PDE5 enzyme, it relaxes specific blood vessels, enhancing blood flow to the penis, which aids in achieving and maintaining an erection when combined with sexual stimulation. For optimal results, avanafil should be taken orally about 15 to 30 minutes before engaging in sexual activity and should not be used more than once a day. It's important to note that avanafil does not offer protection against sexually transmitted infections such as HIV, hepatitis B, gonorrhea, or syphilis. To reduce the risk of infections, it's advised to use effective barrier methods, like latex or polyurethane condoms, during sexual activity. Common side effects of avanafil include headache and flushing. This medication is available solely as a brand-name product and not as a generic variant. Before starting avanafil, consult your healthcare provider to ensure it's safe and suitable for your condition, as this summary is intended for educational purposes and not as a substitute for professional medical advice.