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Fenofibrate is a medication used in conjunction with a suitable diet to help manage high levels of triglycerides and "bad" cholesterol (LDL), while also increasing "good" cholesterol (HDL) in the blood. It belongs to a class of drugs called fibrates and functions by enhancing the breakdown of fats in the bloodstream, which can help reduce the risk of pancreatitis in individuals with extremely high triglyceride levels. However, it may not lower the risk of heart attacks or strokes, so it's essential to discuss its benefits and risks with your doctor. Fenofibrate is available under several brand names, including Antara, Tricor, and Trilipix, and comes in various forms such as capsules and tablets. It is important to note that fenofibrate should not be used with statin medications due to the potential risk of muscle damage and because it does not provide additional cardiovascular benefits compared to statins alone. Common side effects may include liver issues, breathing difficulties, and stomach pain. To enhance the effectiveness of fenofibrate, lifestyle changes such as regular exercise, weight loss for those who are overweight, and smoking cessation are recommended alongside dietary adjustments. Always consult your healthcare provider for personalized advice and before starting any new medication or supplement regimen.